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Free, publicly-accessible full text available July 9, 2026
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Renaud Parentani was one of the leading figures in Quantum Field Theory in curved spacetime, in particular concerning its applications to Hawking-like radiation in analogue models. In this paper dedicated to him, we discuss the characteristic features appearing in the correlation functions in an acoustic black hole formed by a Bose–Einstein condensate, considered as signature of the presence of Hawking radiation in this system.more » « lessFree, publicly-accessible full text available March 4, 2026
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Abstract ObjectivesTo develop CigStopper, a real-time, automated medical billing prototype designed to identify eligible tobacco cessation care codes, thereby reducing administrative workload while improving billing accuracy. Materials and MethodsChatGPT prompt engineering generated a synthetic corpus of physician-style clinical notes categorized for CPT codes 99406/99407. Practicing clinicians annotated the dataset to train multiple machine learning (ML) models focused on accurately predicting billing code eligibility. ResultsDecision tree and random forest models performed best. Mean performance across all models: PRC AUC = 0.857, F1 score = 0.835. Generalizability testing on deidentified notes confirmed that tree-based models performed best. DiscussionCigStopper shows promise for streamlining manual billing inefficiencies that hinder tobacco cessation care. ML methods lay the groundwork for clinical implementation based on good performance using synthetic data. Automating high-volume, low-value tasks simplify complexities in a multi-payer system and promote financial sustainability for healthcare practices. ConclusionCigStopper validates foundational methods for automating the discernment of appropriate billing codes for eligible smoking cessation counseling care.more » « lessFree, publicly-accessible full text available May 2, 2026
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Abstract The Kirkwood-Dirac quasiprobability distribution, intimately connected with the quantum correlation function of two observables measured at distinct times, is becoming increasingly relevant for fundamental physics and quantum technologies. This quasiprobability distribution can take non-positive values, and its experimental reconstruction becomes challenging when expectation values of incompatible observables are involved. Here, we use an interferometric scheme aided by an auxiliary system to reconstruct the Kirkwood-Dirac quasiprobability distribution. We experimentally demonstrate this scheme in an electron-nuclear spin system associated with a nitrogen-vacancy center in diamond. By measuring the characteristic function, we reconstruct the quasiprobability distribution of work and analyze the behavior of its first and second moments. Our results clarify the physical meaning of the work quasiprobability distribution in the context of quantum thermodynamics. Finally, we study the uncertainty of measuring the Hamiltonian of the system at two times, via the Robertson-Schrödinger uncertainty relation, for different initial states.more » « less
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Vernick, Kenneth D (Ed.)Avian malaria is expanding upslope with warmer temperatures and driving multiple species of Hawaiian birds towards extinction. Methods to reduce malaria transmission are urgently needed to prevent further declines. ReleasingWolbachia-infected incompatible male mosquitoes could suppress mosquito populations and releasingWolbachia-infected female mosquitoes (or both sexes) could reduce pathogen transmission if theWolbachiastrain reduced vector competence. We clearedCulex quinquefasciatusof their naturalWolbachia pipientis wPip infection and transinfected them withWolbachia wAlbB isolated fromAedes albopictus. We show thatwAlbB infection was transmitted transovarially, and demonstrate cytoplasmic incompatibility with wild-type mosquitoes infected withwPip from Oahu and Maui, Hawaii. We measured vector competence for avian malaria,Plasmodium relictum, lineage GRW4, of seven mosquito lines (two withwAlbB; three with naturalwPip infection, and two cleared ofWolbachiainfection) by allowing them to feed on canaries infected with recently collected field isolates of HawaiianP.relictum. We tested 73 groups (Ntotal= 1176) of mosquitoes forP.relictuminfection in abdomens and thoraxes 6–14 days after feeding on a range of parasitemias from 0.028% to 2.49%, as well as a smaller subset of salivary glands. We found no measurable effect ofWolbachiaon any endpoint, but strong effects of parasitemia, days post feeding, and mosquito strain on both abdomen and thorax infection prevalence. These results suggest that releasing malewAlbB-infectedC.quinquefasciatusmosquitoes could suppresswPip-infected mosquito populations, but would have little positive or negative impact on mosquito vector competence forP.relictumifwAlbB became established in local mosquito populations. More broadly, the lack ofWolbachiaeffects on vector competence we observed highlights the variable impacts of both native and transinfectedWolbachiainfections in mosquitoes.more » « less
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Abstract Some of the most astonishing and prominent properties of Quantum Mechanics, such as entanglement and Bell nonlocality, have only been studied extensively in dedicated low-energy laboratory setups. The feasibility of these studies in the high-energy regime explored by particle colliders was only recently shown and has gathered the attention of the scientific community. For the range of particles and fundamental interactions involved, particle colliders provide a novel environment where quantum information theory can be probed, with energies exceeding by about 12 orders of magnitude those employed in dedicated laboratory setups. Furthermore, collider detectors have inherent advantages in performing certain quantum information measurements and allow for the reconstruction of the state of the system under consideration via quantum state tomography. Here, we elaborate on the potential, challenges, and goals of this innovative and rapidly evolving line of research and discuss its expected impact on both quantum information theory and high-energy physics.more » « lessFree, publicly-accessible full text available September 1, 2026
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Vereshchagin, G.; Ruffini, R. (Ed.)A method is presented which allows for the numerical computation of the stress-energy tensor for a quantized massless minimally coupled scalar field in the region outside the event horizon of a 4D Schwarzschild black hole that forms from the collapse of a null shell. This method involves taking the difference between the stress-energy tensor for the in state in the collapsing null shell spacetime and that for the Unruh state in Schwarzschild spacetime. The construction of the modes for the {\it in} vacuum state and the Unruh state is discussed. Applying the method, the renormalized stress-energy tensor in the 2D case has been computed numerically and shown to be in agreement with the known analytic solution. In 4D, the presence of an effective potential in the mode equation causes scattering effects that make the the construction of the in modes more complicated. The numerical computation of the in modes in this case is given.more » « less
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Abstract Squamata is the most diverse clade of terrestrial vertebrates. Although the origin of pan-squamates lies in the Triassic, the oldest undisputed members of extant clades known from nearly complete, uncrushed material come from the Cretaceous. Here, we describe three-dimensionally preserved partial skulls of two new crown lizards from the Late Jurassic of North America. Both species are placed at the base of the skink, girdled, and night lizard clade Pan-Scincoidea, which consistently occupies a position deep inside the squamate crown in both morphological and molecular phylogenies. The new lizards show that several features uniting pan-scincoids with another major lizard clade, the pan-lacertoids, in trees using morphology were convergently acquired as predicted by molecular analyses. Further, the palate of one new lizard bears a handful of ancestral saurian characteristics lost in nearly all extant squamates, revealing an underappreciated degree of complex morphological evolution in the early squamate crown. We find strong evidence for close relationships between the two new species and Cretaceous taxa from Eurasia. Together, these results suggest that early crown squamates had a wide geographic distribution and experienced complicated morphological evolution even while the Rhynchocephalia, now solely represented by the tuatara, was the dominant clade of lepidosaurs.more » « less
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